High-Strength Suture

ABSTRACT

A surgical suture is made of an elongate, hollow braid of high strength fibers. The braid defines an elongate, longitudinally-extending, central chamber that is open and without any core material extending therein so that, when a surgeon&#39;s knot is tied with the suture, the cross-sectional shape of the braid collapses upon itself and is reduced in size in response to pressures experienced when the knot is tightened thereby producing a low profile knot that resists slippage. Preferably, the braid is of a size corresponding to a USP size 5-0 to USP size 7 suture and has one or more, preferably a pair, of color contrasting monofilaments woven therein to enhance suture visibility. Methods of making a flattened suture and of utilizing the high strength suture to maintain body tissues in an engaged position to promote healing are also provided.

CROSS-REFERENCE TO RELATED APPLICATION

This application is a Continuation of and claims priority to U.S. patentapplication Ser. No. 10/867,400, filed Jun. 14, 2004, the disclosure ofwhich is incorporated herein by reference in its entirety.

BRIEF SUMMARY OF THE INVENTION

This invention relates to a surgical suture, and more particularly, to ahigh-strength surgical suture providing improved knot tie downcharacteristics that enable surgeons to form low profile knots havingsuperior knot security.

Sutures are elongate implant devices used to maintain body tissuestogether to promote natural healing and/or to compress blood vessels tostop bleeding. Sutures are typically knotted to hold divided wound edgestogether, and the mechanical performance of surgeons' knots has aneffect on proper wound healing. If a suture and/or knot fails, it shouldfail due to breakage, not due to knot slippage. Examples of tests fordetermining the mechanical performance of knotted sutures are discussedin the article by Zimmer et al. titled “Influence of Knot Configurationand Tying Technique on the Mechanical Performance of Sutures” publishedin The Journal of Emergency Medicine, Volume 9, pages 107-113, 1991.

Sutures are manufactured in various sizes, typically according tostandards established by the United States Pharmacopeia (USP). Suturesize is typically determined by the diameter or gauge of the roundcross-section of the suture. See Table 1 provided below.

TABLE 1 Metric Diameter, USP-Size Gauge No. Min-Max (mm) 12-0  0.010.001-0.009 11-0  0.1 0.010-0.019 10-0  0.2 0.020-0.029 9-0 0.30.030-0.039 8-0 0.4 0.040-0.049 7-0 0.5 0.050-0.069 6-0 0.7 0.070-0.0995-0 1.0 0.100-0.149 4-0 1.5 0.150-0.199 3-0 2.0 0.200-0.249 2-0 3.00.300-0.339 0 3.5 0.350-0.399 1 4.0 0.400-0.499 2 5.0 0.500-0.599 3 and4 6.0 0.600-0.699 5 7.0 0.700-0.799 6 8.0 0.800-0.899 7 9.0 0.900-0.9998 10.0 1.000-1.099 9 11.0 1.100-1.199 10  12.0 1.200-1.299

Surgical sutures, particularly those of USP size 5-0 and greater, havebeen constructed having a core of fibers extending within an outerbraided cover or sheathing of fibers. See prior art suture 100illustrated in FIG. 1. Suture 100 has an outer braided sheathing offibers 102 surrounding a twisted core of fibers 104 and has a roundcross section (ie., the x dimension equals the y dimension asillustrated in FIG. 1). Examples of surgical sutures having cores arealso provided by U.S. Pat. Nos. 4,946,467 issued to Ohi et al.,4,546,769 issued to Planck et al., and 6,045,571 issued to Hill et al.The core fibers are used to increase the strength of the suture and toprovide the suture with a rounded cross-section. Needles used withsutures typically have a round cross-section and make round holes, andit has been believed desirable to make the cross-section of sutures asround as possible to fill the round holes to reduce bleeding. Thus,cores enable the roundness of the cross-section of the suture to bemaintained during use. However, such sutures have experienced problemsrelating to the different elongation to break between the core and covermaterials and problems relating to the core popping through the cover.

Surgical sutures have been made of high strength materials. For example,U.S. Pat. No. 5,318,575 issued to Chesterfield et al. disclosesso-called “high-strength” fibers to manufacture spiroid and hollowbraided surgical sutures having cores. An example of a high strengthfiber is ultra-high molecular weight, extended-chain polyethylenehigh-tenacity fiber sold under the tradename “SPECTRA”. U.S. Pat. Nos.4,790,850 issued to Dunn et al., 4,792,336 issued to Hlavacek et al.,5,628,756 and 5,540,703 issued to Barker, Jr. et al. and 5,456,722issued to McLeod et al. disclose high-strength, ultra-high molecularweight polyethylene fibers in relatively large diameter surgical cablesused as prosthetic ligaments, tendon implants, and the like. Also seeU.S. Pat. No. 6,716,234 B2 issued to Grafton et al. and U.S. PatentApplication Publication Nos. US 2003/0050667 A1 and US 2003/0139775 A1which disclose high-strength sutures made in part of ultra-highmolecular weight polyethylene fibers, such as those sold under thetrademarks “SPECTRA” and “DYNEEMA”.

Fibers of contrasting colors have been utilized in surgical sutures toenhance suture visibility, and suture handling properties have beenimproved with coatings including various lubricants and the like. Forexample, U.S. Pat. No. 3,949,755 issued to Vauquois discloses a braidedsuture having fibers of contrasting colors, and U.S. Pat. Nos. 4,043,344issued to Landi et al., 4,047,533 issued to Perciaccante et al., and5,019,093 issued to Kaplan et al. disclose various coatings utilized onsutures.

While the aforementioned sutures may be satisfactory for their intendedpurposes, there is a need for an improved surgical suture that is madeof high strength fibers and that possesses improved knot-tying andknot-security properties. To this end, a lubricious, multi-filamentsuture, permitting the construction of a secure knot having a lowprofile and improved knot security, is desired. In addition, the sutureshould have enhanced visibility and handling characteristics.

The invention addresses the foregoing objects by providing a surgicalsuture made of an elongate woven braid of fibers that include ultra-highmolecular weight polyethylene fibers. The braid of fibers is hollow andis without any core material extending therein. The absence of a coreenables the cross-sectional shape of the braid of fibers to becomealtered in response to pressures exerted thereon when the suture isknotted so that a knot having a low profile is formed. Preferably, thebraid of fibers is of a size corresponding to a suture with the rangefrom about USP sizes 5-0 to 7 (ie., the suture has a diameter in therange from about 0.100 to 0.999 mm).

According to another aspect of the present invention a method isprovided for maintaining body tissues in an engaged position to promotehealing. A suture is used to stitch the body tissues together and atleast one knot is tied with the suture to hold the body tissues togetherfor at least a predetermined period of time that is required for properhealing. The suture is an elongate woven braid of fibers includingultra-high molecular weight polyethylene fibers, and the braid of fibersis hollow without a core material extending therein. During the tyingstep, the cross-sectional shape of the braid of fibers changes inresponse to pressures experienced during knotting thereby providing aknot having a low profile. Preferably, the suture has an initial size,before knotting, corresponding to a USP size 5-0 to USP size 7 suture(ie., a diameter between about 0.100 to 0.999 mm).

BRIEF DESCRIPTION OF THE DRAWINGS

FIG. 1 is a cross-sectional view of a suture having a core according tothe prior art;

FIG. 2 is a cross-sectional view of a suture without a core according tothe present invention;

FIG. 3 is a cross-sectional view of a flattened suture without a coreaccording to the present invention;

FIG. 4-6 are views of a suture knot testing assembly; and

FIG. 7 is a view of a knot showing the dimensions measured to determinethe volume of the knot.

DETAILED DESCRIPTION

The invention relates to a surgical suture made of an elongate, hollowbraid of high strength fibers and a method of making the suture. Inaddition, the invention relates to a method of utilizing the highstrength suture to maintain body tissues in an engaged position topromote healing.

Typically, surgical sutures are made to have round cross-sections ofsizes corresponding to those identified on the size chart provided abovein Table 1. Sutures made of a hollow braid of fibers that correspond toa USP size 5-0 to a USP size 7 suture include a reinforcing corematerial extending within the braid. See FIG. 1. The core material fillsthe central open void within the braid so that a desired roundcross-section is maintained throughout use of the suture as discussedabove. For examples of such sutures, see the disclosures provided byU.S. Pat. Nos. 5,318,575 issued to Chesterfield et al., 6,045,571 issuedto Hill et al., and 6,716,234 B2 issued to Grafton et al. and U.S.Patent Application Publication Nos. US 2003/0050667 A1 and US2003/0139775 A1. Sutures smaller than USP size 5-0 sutures are too smallto have central open voids and have been made without a core materialsimply because adequate space for a core material is not available. U.S.Pat. Nos. 5,628,756 and 5,540,703 issued to Barker, Jr. et al. and5,456,722 issued to McLeod et al. disclose large braided surgical cableshaving diameters of at least 1 to 3 mm. These braids are made of 9 to 13picks per inch and from large denier ends (ie., minimum 650 denier) onan eight carrier braider providing a total minimum denier of 5200 denier(ie., 8×650). Thus, such large braids also provide no void or open spacein which a core material can be extended.

As best illustrated in FIGS. 2 and 3, the suture 10 according to thepresent invention is a hollow braid of fibers 12 of a size within arange of USP size 5-0 to USP size 7 (ie., has a diameter between about0.1 to about 0.999 mm as measured when in a round condition asillustrated in FIG. 2). Unlike prior art sutures of like sizes, thesuture 10 is coreless without any core material extending within thehollow braid 12. Thus, the braid 12 defines an elongate,longitudinally-extending, central chamber 14 that is without a corematerial extending therein. FIG. 2 illustrates a cross-section of suture10 when disposed in a circular configuration. However, the suture 10according to the present invention can also be provided in an oval,relatively flat, or tape-like configuration as illustrated in FIG. 3since the braid 12 is coreless and can collapse upon itself. Forpurposes of this application, the size of suture 10 corresponds todiameter measurements taken when suture 10 is disposed in asubstantially circular cross-sectional configuration, such as shown inFIG. 2.

The coreless, hollow-braided suture 10 provides improved knot-tying andknot-security capabilities. When a knot is tied with suture 10, thecross-sectional shape and size of suture 10 at the knot changes andbecomes reduced since the pressure exerted during the formation of theknot causes the suture 10 to collapse upon itself at the knot site. Thisreduces the length, width, volume and mass of the knot providing it witha profile that is significantly less than that of a similarly sizedprior art suture having a core. Thus, the presence of the open centralchamber 14 and the absence of any core material therein for the abovereferenced range of suture size permits the ready formation of lowprofile knots that remain secure without slippage for an extended periodof time. This results in significant advantages relative to knots tiedwith prior art braided sutures that have a core material, since thepresence of a core material limits the ability of a prior art suture tocollapse upon itself during knot tying and tightening actions.

Preferably, the braid 12 is made of high strength fibers 16, such asultra-high molecular weight polyethylene fibers, to compensate for theabsence of a core material. For example, braid 12 can be made entirely(100%) of ultra-high molecular weight polyethylene fibers, oralternatively, can include one or more strands of a differentfiber/filament. Preferably, the high strength fibers 16 in the braid 12form at least 75%, or 90%, of the total fibers of the braid 12, so thata suture 10 having high strength is provided despite the absence of acore material.

In a preferred embodiment, the suture 10 includes one or more,preferably two, strands of a color contrasting monofilament 18 toenhance suture visibility during surgery. The ultra-high molecularweight polyethylene fibers 16 are typically white or translucent. Thus,the suture 10 preferably includes a strand or stands of a monofilament18 that is of a highly-visible contrasting color and that is woven inthe braid 12 with the ultra-high molecular weight polyethylene fibers16. As an example, the monofilament 18 can be a deep blue color.Alternatively, strands of other colors can be utilized. Preferably, thecolor-contrasting monofilament 18 is a color-extruded monofilament ofpolypropylene or polydioxanone. To this end, preferably a colorant orpigment is compounded into a resin before the resin is extruded to forma color-extruded monofilament. Thus, preferably the monofilament 18 isnot subjected to a post-formation dyeing step as typically required forpolyester and nylon materials.

By way of example, the braid of suture 10 can include 8, 16, 24, or 32ends braided together at approximately 50-70 pics per inch. The variousnumbers of ends used are for the purpose of changing the resultant sizeof the finished braid while holding the denier constant. Preferably, thesuture 10 includes only ultra-high molecular weight polyethylene fibers16 and one or more, preferably a pair, of color-contrastingmonofilaments 18 of a color-extruded monofilament of polypropylene orpolydioxanone. As a specific example, the braid 12 can include sixteenends braided together with fourteen ends being ultra-high molecularweight polyethylene fibers 16 and a pair of ends being color-contrastingpolypropylene monofilaments 18 located at opposed positions within thebraid. Preferably the color contrasting monofilaments 18 comprise nomore than 25% of the total fibers of the braid 12. In addition,preferably the suture 10 is of a size within a range of USP size 5-0 toUSP size 7 (ie., has a diameter of at least about 0.1 mm and less than1.0 mm), and optionally, the suture 10 can be coated with wax, silicone,silicone rubber, PTFE, PBA, ethyl cellulose or like coating to improvehandling, lubricity of the braid, abrasion resistance, and likecharacteristics.

A method of maintaining body tissues in an engaged position to promotehealing is also provided by the present invention. To this end, a USPsize 5-0 to USP size 7 suture is utilized to stitch body tissuestogether and a surgeon's knot is tied with the suture to hold the bodytissues together for at least a predetermined period of healing time. Asdiscussed above, the suture 10 is an elongate woven braid of fibersincluding ultra-high molecular weight polyethylene fibers, and the braidof fibers is hollow and has an elongate, longitudinally-extending,central chamber that is open and without a core material extendingtherein. Thus, during knot tying, the braid 12 at the site of the knotis reduced in size, diameter, and shape in response to pressuresexperienced during tying thereby producing a knot having a reduced mass,volume, and profile.

EXAMPLES

An example of a careless braided suture according to the invention andtests with respect to the dimensions and security of knots formed withthe suture are provided below and are contrasted with sutures havingcores according to the prior art. General information concerning braidconstruction is disclosed by U.S. Pat. No. 6,045,571 issued to Hill etal., and general information concerning suture knot construction andtests of mechanical performance of knots are disclosed in the article ofZimmer et al. titled “Influence of Knot Configuration and TyingTechnique on the Mechanical Performance of Sutures” published in 1991 inThe Journal of Emergency Medicine, Volume 9, pages 107-113. Thedisclosures of both of these references are incorporated herein byreference.

For testing purposes, a USP size 2 braided suture according to theinvention was made with a sixteen-carrier New England Butt braiderNo. 1. Each carrier held 110 denier DYNEEMA ultra high molecular weightpolyethylene fiber, and the braider was equipped with a cross shaft gearof 82 and a lower change gear of 24. The gears provide an expected pickcount of 62 picks per inch (PPI). The braided suture according to thepresent invention was flattened by being passed over and under tworollers before transition to a smaller step roll (1.185 inch) and fivepasses to a roller before final take up on an iron head. The rollers canbe made of metal or ceramic, and the geometry of the rollers to eachother serve to flatten the braid. See FIG. 3 for an example of the shapeof the flattened braid.

Tables 2 and 3, provided below, show the effects on suture diameter offlattening the braided suture of the invention. To this end, Table 2provides diameter measurements in mils of fifteen samples of the sutureaccording to the invention that were not subjected to the abovereferenced flattening procedures, and Table 3 provides diametermeasurements in mils of fifteen samples of the suture according to theinvention that were subjected to the above referenced flatteningprocedures. Low diameters, high diameters and average diameters aremeasured for each sample and overall averages are listed below the lastline of the tables.

TABLE 2 NORMAL BRAID (see FIG. 2) Low High Average Diameter DiameterDiameter (MIL) (MIL) (MIL) 22.9 24.4 23.7 23.0 24.3 23.7 22.7 24.3 23.523.0 24.3 23.7 23.4 24.7 24.1 23.1 24.5 23.8 23.1 24.7 23.9 22.7 24.523.6 22.9 24.4 23.7 23.2 24.7 24.0 23.5 25.0 24.3 23.1 24.6 23.9 23.124.6 23.9 23.1 24.7 23.9 22.9 24.8 23.9 Ave.: 23.0 24.6 23.8

TABLE 3 FLATTENED BRAID (see FIG. 3) Low High Average Diameter DiameterDiameter (MIL) (MIL) (MIL) 20.0 26.3 23.2 21.2 23.2 22.2 20.0 26.7 23.420.8 27.2 24.0 20.4 27.3 23.9 19.8 27.1 23.5 20.2 27.0 23.6 20.6 25.122.9 20.7 27.4 24.1 19.9 26.2 23.1 20.5 22.9 21.7 20.2 27.8 24.0 20.327.4 23.9 20.1 27.6 23.9 20.0 27.9 24.0 Ave.: 20.3 26.5 23.4

For testing purposes, a USP size 2 braided suture having a coreaccording to the prior art was also made with a sixteen-carrier NewEngland Butt braider No. 1. Each carrier held 110 denier DYNEEMA ultrahigh molecular weight polyethylene fiber. The braid was formed as acover over a center core of a three ply of 220 denier DYNEEMA ultra highmolecular weight polyethylene fiber. The braider was equipped with across shaft gear of 82, a lower change gear of 24, and a small step roll(1.185 inch). The gears provide an expected pick count of 62 picks perinch (PPI).

Various tests were run with the above referenced suture according to theinvention and the above referenced prior art suture having a core. Inaddition, different types of knots were tested for the sutures. As willbe discussed in greater detail, the tests show that the coreless sutureaccording the invention can be used to create knots of lower profile andof better security than the comparative prior art sutures.

The test utilized a MTS Reliance RT/5 test frame with a 500 N load cellinstalled on the MTS Reliance RT/5 test frame. For each knot 30 to beevaluated, a suture was tied around a 4.75 inch roll of paper 20 coveredwith a 0.25 inch layer of foam rubber 22 as illustrated in FIG. 4. Allknots tested included a square knot followed by one or more square orgranny throws. Beginning with the second throw of each knot, equaltension was applied to each throw of the knot configuration by thepneumatic jaws 24 of the MTS Reliance RT/5 test frame with an extensionrate of 500 mm/min to a final tension of 6.2 lbf, which represents 80%of the LISP knot pull tensile strength requirement of the suture.Thereafter, the ears 26 of the knot 30 were trimmed to approximately 3mm, and the suture was removed from the roll 20 by cutting the suture atthe midpoint 28 opposite the knot 30 at the back of the roll 20. SeeFIG. 5. The knot dimensions of the removed suture was then measured andits knot security tested on an Instron 3300 tensile strength instrument.See FIGS. 6 and 7.

The dimensions of each knot 30 was measured on a Nikon MeasurescopeMM-11 microscope. The knot 30 was placed on the plate of the microscopewith suture ends 32 and 34 extended, and weights were used to hold theknot in a fixed position. The width and length of the knot was measuredin inches with the microscope along x-coordinate and y-coordinatedirections. See FIG. 7.

Patient side knot security was tested for each knot 30 by placing thesuture ends, 32 and 34, of the knot between fiber grips 36 of theInstron tensile strength instrument. See FIG. 6. The tensile strengthwas tested, and it was observed whether or not the knot slipped (S) orbroke (B). The peak load observed before breakage or slippage wasrecorded as well as the mode of separation, ie., S or B.

The results of the tests are shown in the following Tables. Table 4provides the results of tests on the present invention, Table 5 providesthe results of tests on the above described comparative suture having acore, and Table 6 provides the results of tests on a poly-blend suturehaving a core made according to U.S. Pat. No. 6,716,234 B2 issued toGrafton et al. The tested knots include a two throw square knot withadditional square throws. The standard convention for a square throw “=”is used. For example, a knot type identified as “1=1=1=1” is a two throwsquare knot (“1=1”) with two additional square throws (“=1=1”), and aknot type identified as “1=1=1=1=1” is a two throw square knot (“1=1”)with three additional square throws (“=1=1=1”). Table 7 provides asummary of the knot dimension and knot security measurements listed indetail in Tables 4-6.

TABLE 4 Knot Test Data for Suture of Invention Break/ Trial Slip HeightVolume Knot Type No. Security (lb) (in) (in³) × 10³ 1 = 1 = 1 = 1 1Break 29.7 0.1200 0.652 2 Slip 25.5 0.1344 0.599 3 Break 29.5 0.11140.516 4 Slip 25.7 0.1279 0.724 5 Break 29.4 0.1014 0.639 6 Slip 20.90.1509 0.591 7 Slip 18.7 0.1152 0.786 8 Slip 23.7 0.1527 0.615 9 Slip25.3 0.1235 0.709 10  Slip 23.8 0.1100 0.801 Ave. 30% 25.2 0.1247 0.663Break 1 = 1 = 1 = 1 = 1 1 Break 31.2 0.1573 0.922 2 Break 29.8 0.18981.067 3 Break 29.3 0.1643 1.232 4 Slip 28.0 0.1238 1.277 5 Break 29.30.1572 1.091 6 Break 30.1 0.1717 1.179 7 Break 26.7 0.1432 1.207 8 Break29.7 0.1512 1.847 9 Break 29.7 0.1720 1.308 10  Break 27.9 0.1552 0.966Ave. 90% 29.2 0.1586 1.209 Break

TABLE 5 Knot Test Data for Comparative Suture having a Core Break/ TrialSlip Height Volume Knot Type No. Security (lb) (in) (in³) × 10³ 1 = 1 =1 = 1 1 Slip 26.4 0.1479 0.979 2 Slip 27.4 0.1378 1.232 3 Slip 24.90.1374 1.017 4 Slip 25.6 0.1177 0.897 5 Slip 24.8 0.1230 0.911 6 Slip23.9 0.1485 1.323 7 Slip 24.4 0.1678 1.323 8 Slip 25.0 0.1728 1.030 9Slip 21.7 0.1672 1.097 10  Slip 21.6 0.1947 1.949 Ave. 0% 24.6 0.15151.176 Break 1 = 1 = 1 = 1 = 1 1 Slip 30.3 0.2244 1.331 2 Break 34.50.2044 2.266 3 Break 35.3 0.2216 2.008 4 Break 34.1 0.1631 1.082 5 Break37.2 0.1759 0.856 6 Break 33.9 0.2313 1.207 7 Slip 35.2 0.1979 1.220 8Break 35.1 0.1701 1.203 9 Slip 31.6 0.2245 0.847 10  Break 34.8 0.17740.978 Ave. 70% 34.2 0.1991 1.300 Break

TABLE 6 Knot Test Data for suture made according to U.S. Pat. No.6,716,234 B2 Break/ Trial Slip Height Volume Knot Type No. Security (lb)(in) (in³) × 10³ 1 = 1 = 1 = 1 = 1 1 Slip 24.3 0.1900 1.249 2 Break 27.50.1869 0.546 3 Break 26.7 0.1826 0.733 4 Slip 21.5 0.1896 1.274 5 Slip19.6 0.2045 0.751 6 Slip 26.8 0.1512 1.240 7 Slip 22.3 0.1891 0.813 8Break 30.8 0.1776 1.046 9 Slip 25.7 0.1772 1.056 10  Slip 18.7 0.19191.205 Ave. 30% 24.4 0.1841 0.991 Break

TABLE 7 Knot Dimension and Security Summary Two Throw Square Knot withAdditional Square Throws Knot: 1 = 1 = 1 = 1 Knot: 1 = 1 = 1 = 1 = 1Height Volume Height Volume Suture (in) (in³) × 10³ Security (in) (in³)× 10³ Security Invention 0.1247 0.663 30% 0.1586 1.209 90% (coreless)Compara- 0.1515 1.176  0% 0.1991 1.300 70% tive Example (w/core)Poly-blend NA NA NA 0.1841 0.991 30% with core

The results of tests for knots that include a two throw square knot withone or more additional granny throws are provided in Tables 8-9. To thisend, the standard convention for a granny throw “x” is used. Forexample, a knot type identified as “1=1x1” is a two throw square knot(“1=1”) with an additional granny throw (“x1”), a knot type identifiedas “1=1x1x1” is a two throw square knot (“1=1”) with two additionalgranny throws (“x1x1”), and a knot type identified as “1=1x1x1x1” is atwo throw square knot (“1=1”) with three additional granny throws(“x1x1x1”). Table 8 provides the results of tests on the presentinvention, Table 9 provides the results of tests on the above describedcomparative suture having a core, and Table 10 provides a summary of theknot dimension and knot security measurements listed in detail in Tables8 and 9.

TABLE 8 Knot Test Data for Suture of Invention Trial Break/Slip HeightVolume Knot Type No. Security (lb) (in) (in³) × 10³ 1 = 1 × 1 1 Slip12.8 NA NA 2 Slip 13.3 NA NA 3 Slip 13.1 NA NA 4 Slip 13.5 NA NA 5 Slip13.0 NA NA 6 Slip 12.3 NA NA 7 Slip 15.4 NA NA 8 Slip 13.8 NA NA 9 Slip14.0 NA NA 10 Slip 11.9 NA NA Ave. 0% Break 13.3 1 = 1 × 1 × 1 1 Slip21.5 0.1363 0.808 2 Slip 22.3 0.1023 0.799 3 Break 26.2 0.1425 1.248 4Slip 20.7 0.1125 1.048 5 Slip 22.5 0.1405 0.495 6 Slip 23.9 0.1578 0.9277 Slip 24.4 0.1316 0.945 8 Slip 26.3 0.1318 0.952 9 Slip 18.3 0.14251.057 10 Slip 14.7 0.1267 1.105 Ave. 10% Break 22.1 0.1325 0.939 1 = 1 ×1 × 1 × 1 1 Break 30.7 0.1514 0.890 2 Break 28.6 0.1657 0.954 3 Break30.0 0.1935 0.944 4 Slip 26.9 0.2179 1.140 5 Break 30.5 0.1470 1.086 6Break 27.8 0.1563 0.955 7 Break 26.3 0.1537 1.316 8 Break 27.8 0.14921.377 9 Break 29.6 0.1889 1.136 10 Break 30.3 0.1506 1.675 Ave. 90%Break 28.9 0.1674 1.147

TABLE 9 Knot Test Data for Comparative Example with core Break/ TrialSlip Height Volume Knot Type No. Security (lb) (in) (in³) × 10³ 1 = 1 ×1 1 Slip 14.9 NA NA 2 Slip 9.1 NA NA 3 Slip 15.2 NA NA 4 Slip 14.1 NA NA5 Slip 13.2 NA NA 6 Slip 14.1 NA NA 7 Slip 7.1 NA NA 8 Slip 13.7 NA NA 9Slip 13.0 NA NA 10  Slip 14.8 NA NA Ave. 0% 12.9 Break 1 = 1 × 1 × 1 1Slip 24.6 0.1566 1.582 2 Slip 26.0 0.1315 1.136 3 Slip 25.4 0.1463 1.5334 Slip 25.4 0.1366 1.073 5 Slip 27.6 0.1245 1.443 6 Slip 22.1 0.16061.591 7 Slip 24.6 0.1503 1.505 8 Slip 22.9 0.1751 1.378 9 Slip 25.10.1391 1.826 10  Slip 21.3 0.1197 1.381 Ave. 0% 24.5 0.1440 1.445 Break1 = 1 × 1 × 1 × 1 1 Slip 36.0 0.1739 1.698 2 Break 35.0 0.1991 1.370 3Slip 36.0 0.2065 1.485 4 Break 35.1 0.1699 1.867 5 Slip 29.0 0.19062.656 6 Break 34.7 0.1963 2.467 7 Slip 30.2 0.1920 2.490 8 Slip 32.40.1763 2.427 9 Slip 28.0 0.2035 3.356 10  Break 32.1 0.2015 2.634 Ave.40% 32.9 0.1910 2.245 Break

TABLE 10 Know Dimension and Security Summary Two Throw Square Knot withAdditional Granny Throws Knot: 1 = 1 × 1 × 1 Knot: 1 = 1 × 1 × 1 × 1Height Volume Height Volume Suture (in) (in³) × 10³ Security (in) (in³)× 10³ Security Invention 0.1325 0.939 10% 0.1674 1.147 90% (coreless)Compara- 0.1440 1.445  0% 0.1910 2.245 40% tive Example (w/core)

As indicated by the results in the above referenced Tables, the carelessbraided suture of the invention permits surgeons to construct knots thatsnug down to a lower profile (ie., height) than that permitted by thecomparative sutures having cores. In addition, the results demonstratethat the coreless braided suture of the invention provides better knotsecurity (ie., less slippage).

While preferred sutures and methods of use have been described, variousmodifications, alterations, and changes may be made without departingfrom the spirit and scope of the invention as defined in the appendedclaims.

1. A surgical suture comprising: an elongate woven braid of fibersincluding ultra-high molecular weight polyethylene fibers, said braid offibers being hollow and defining an elongate, longitudinally-extending,open central chamber without a core material extending therein, whereinsaid suture is a USP size 5-0 to USP size 7 suture having a diameter inthe range between 0.100 mm to 0.999 mm, and wherein at least 75% of saidfibers of said braid are said ultra-high molecular weight polyethylenefibers, and wherein said chamber is sufficiently large to enable across-sectional shape of said braid of fibers to collapse upon itself inresponse to pressures experienced when the suture is knotted.
 2. Asurgical suture according to claim 1, wherein said suture has asubstantially circular round cross-sectional configuration whichcollapses in response to pressures experienced when the suture isknotted.
 3. A surgical suture according to claim 2, wherein the chamberhas a cross-sectional diameter that is substantially larger than adiameter of the fibers.
 4. A surgical suture according to claim 2,wherein the denier of each of said fibers is no greater than about 110denier.
 5. A surgical suture according to claim 2, wherein said braid offibers includes at least one strand of a color-contrasting monofilamentof a color different from that of said ultra-high molecular weightpolyethylene fibers.
 6. A surgical suture according to claim 5, whereinsaid color-contrasting monofilament is a monofilament of polypropyleneor polydioxanone and is woven with said plurality of ultra-highmolecular weight polyethylene fibers to form said braid of fibers.
 7. Asurgical suture according to claim 6, wherein said braid consists ofsixteen ends, of which fourteen ends are ultra-high molecular weightpolyethylene fibers and two ends are color-contrasting monofilaments ofpolypropylene.
 8. A surgical suture according to claim 2, wherein saidbraid includes 8, 16, 24, or 32 ends braided together at approximately50-70 pics/inch.
 9. A method for maintaining body tissues in an engagedmanner to promote healing comprising: utilizing a USP size 5-0 to USPsize 7 suture having a diameter in the range from 0.100 mm to 0.999 mmto stitch said body tissues together, said suture being an elongatewoven braid of fibers including ultra-high molecular weight polyethylenefibers, said braid of fibers being hollow and having an elongate,longitudinally-extending, open central chamber without a core materialextending therein during the step of stitching said body tissuestogether, wherein at least 75% of said fibers of said braid are saidultra-high molecular weight polyethylene fibers; and tying at least oneknot with said suture to hold said body tissues together for at least apredetermined period of time, wherein said chamber is sufficiently largesuch that, during said tying step, a cross sectional shape of said braidcollapses upon itself in response to pressures experienced duringknotting.
 10. A method according to claim 9, wherein said suture has asubstantially circular round cross-sectional configuration whichcollapses in response to pressures experienced when the suture isknotted.
 11. A method according to claim 10, wherein the chamber has across-sectional diameter that is substantially larger than a diameter ofthe fibers.
 12. A method according to claim 10, wherein the denier ofeach of said fibers is no greater than about 110 denier.
 13. A methodaccording to claim 10, wherein said braid of fibers includes at leastone strand of a color-contrasting monofilament of a color different fromthat of said ultra-high molecular weight polyethylene fibers.
 14. Amethod according to claim 13, wherein said color-contrastingmonofilament is a monofilament of polypropylene or polydioxanone and iswoven with said plurality of ultra-high molecular weight polyethylenefibers to form said braid of fibers.
 15. A method according to claim 14,wherein said braid consists of sixteen ends, of which fourteen ends areultra-high molecular weight polyethylene fibers and two ends arecolor-contrasting monofilaments of polypropylene.
 16. A method accordingto claim 10, wherein said braid includes 8, 16, 24, or 32 ends braidedtogether at approximately 50-70 pics/inch.